For virologically suppressed adult patients with HIV-1. See Full Indication.

JULUCA | Milestones in the Treatment of HIV-1

1987

Early Antiretroviral Therapy (ART):

Zidovudine (AZT) is the first medication approved for the treatment of HIV-11

1996

HAART:

Combinations of certain ARTs are effective regimens, but may require multiple pills taken more than once a day1

2006

Once-Daily STRs:

Single-tablet, 3-drug regimens achieve virologic suppression with 1 pill taken once per day1

2017

A Complete, Dolutegravir-Based, 2-Drug Regimen:

The first dolutegravir-based, 2-drug regimen in 1 tablet indicated for virologically suppressed adult patients with HIV-1

HAART=highly active antiretroviral therapy; STRs=single-tablet regimens.

Many Patients Could Be on ART for 40 or More Years2

How can limiting the number of medications in an HIV-1 regimen impact a patient over the length of treatment?

References:

  1. FDA-approved HIV medicines. https://hivinfo.nih.gov/understanding-hiv/fact-sheets/fda-approved-hiv-medicines. Accessed September 21, 2020.
  2. Antiretroviral Therapy Cohort Collaboration. Survival of HIV-positive patients starting antiretroviral therapy between 1996 and 2013: a collaborative analysis of cohort studies. Lancet HIV. 2017;4(8):e349-e356.

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